The world’s first clinically validated lysin for body odour control.

ArcherZyme® is fast-acting: it is designed to address the factors that cause underarm odour while preserving the rest of the underarm microbiome. in-cosmetics Asia 2025 Gold Award winner.

Underarm odour is linked to specific bacteria.

Conventional deodorants either act broadly (alcohol, antimicrobials), block sweat (aluminium), or mask. ArcherZyme® is designed to address the bacteria associated with underarm odour, including S. hominis, while leaving the rest of the skin’s microbiome in balance.

ArcherZyme® · body odour

Good community: undisturbed S. hominis ArcherZyme protein

ArcherZyme® is a phage-derived enzyme that recognises and selectively acts on bacteria associated with underarm odour, such as S. hominis, while leaving the rest of the skin community undisturbed.

Fast-acting, clinically validated

Fast-acting, with all-day freshness from a single use.

ArcherZyme® is built for speed. In the lab, it measurably reduces odour-associated bacteria within 10 minutes of application. In the clinical study, the first odour reading was taken at 2 hours, where the treated side was already ~61% fresher, and we expect future studies with earlier measurement points to show the benefit sooner still.

~0%

odour reduction by the first clinical reading at 2 hours (vs unchanged control)

~0%

odour reduction still measured at 24 hours

would buy a product with ArcherZyme®

reported lower baseline odour after one week

Lab: odour-associated bacteria reduced within 10 minutes (in vitro)

100% noticed control lasting 2–6h after one use

>85% rated performance “excellent”

S. hominis selectively reduced; Cutibacteria & Corynebacteria preserved

Clinical study: n=27, split-axilla design (one underarm treated, one control), single supervised application + one week daily home use. Odour scored by a 6-person sniffer panel (0–10 scale) at 0h, 2h, 8h and 24h, plus qPCR microbiome analysis. The 2-hour point was the first measurement; earlier time points were not assessed in this study. 10-minute activity is from in vitro testing. van Steensel et al., manuscript accepted.

For formulators

For formulators.

Request a meeting

Evaluation samples are available for purchase, typically after an introductory call, never a free giveaway. Once you have a sample in hand, our team works alongside you, at no charge, to turn it into a successful formulation.

Dosage	0.01%
Appearance	White, odourless freeze-dried powder
Formats	Roll-on, spray, body oil, lotion
Processing	Cold-process friendly
Stability	24 months at 25°C (testing ongoing)
Safety	Non-irritant (IS 4011:2018; OECD 439); aluminium-free
IP	MIT-licensed WO2022104171

Formulating with our actives

Built to drop into your formula.

Both actives are protein-based, so formulation friendliness comes down to protecting the protein. Below is the practical guidance our team shares with formulators. Full compatibility tables and stability support come with a sample.

Recommended pH 5.5–8.5Add cold in the final phase at ≤30–40°C; gentle mixing to avoid shear and foaming.

Plays well with

Base & solvents: Buffered water, propanediol, propylene glycol
Humectants: Glycerol, trehalose, dextran, amino acids
Gelling agents: Carbomer 940, HEC, HPMC, chitosan
Thickeners: Cellulose gum, xanthan gum (minimal)
Surfactants: Polysorbate 20/60/80, poloxamer 184/188, decyl/coco-glucoside (minimal)
Oils: Caprylic/capric triglyceride, squalane, dimethicone, mineral oil
Stabilisers: Trehalose, tocopherol, sodium ascorbyl phosphate (EDTA: SmartArrow® only)

Best avoided

Alcohols: Ethanol, isopropanol: denature proteins even at low levels
Strong ionic surfactants: SLS, SLES (CAPB only if validated): denaturing
Reactive aldehydes: Citral, cinnamaldehyde, benzaldehyde: react with protein
Reducing sugars: Glucose, fructose, lactose: Maillard reaction over time
Alkaline soap systems: pH >9 irreversibly unfolds protein
Inorganic thickeners: Polyphosphates, clays: can bind/adsorb protein

Reference formulationBody oil (anhydrous)

Caprylic/capric triglyceride	Carrier oil	80–85% w/w
Jojoba seed oil	Natural oil	10% w/w
Silica dimethyl silylate	Rheology modifier	5% w/w
ArcherZyme®	Active	1% w/w

Reference formulation by Chaks Cosmetic Design & Services Pte. Ltd. Illustrative only, not final or exhaustive. Guidance is based on formulation principles and compatibility observations for enzyme-based actives. Confirm stability in your intended product matrix; our team will support you.

Claim directions

Marketing claims your brand team can build on.

Performance

Clinically evaluated all-day freshness
From application to action in minutes (in vitro)
100% body odour control after one use

Safety

Zero irritation, dermatologically tested
Microbiome-safe innovation
Aluminium-free formula

Sustainability

Micro-dose (0.01%), macro performance
Precision-fermentation derived
Energy-efficient production

Positioning

Advanced molecular engineering
High-performance enzymatic technology
Premium biotech for daily confidence

Claim directions are starting points for partner marketing. Final claims must be substantiated and reviewed for the target market and product format.